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Lee Techner Selected Research

alvimopan

8/2014Alvimopan accelerates gastrointestinal recovery after radical cystectomy: a multicenter randomized placebo-controlled trial.
6/2014Alvimopan, a peripherally acting μ-opioid receptor antagonist, is associated with reduced costs after radical cystectomy: economic analysis of a phase 4 randomized, controlled trial.
5/2012Alvimopan for acceleration of GI recovery after bowel resection.
4/2011Impact of alvimopan (entereg) on hospital costs after bowel resection: results from a large inpatient database.
9/2010Alvimopan for the management of postoperative ileus after bowel resection: characterization of clinical benefit by pooled responder analysis.
11/2008Gastrointestinal tract recovery in patients undergoing bowel resection: results of a randomized trial of alvimopan and placebo with a standardized accelerated postoperative care pathway.
10/2007Alvimopan accelerates gastrointestinal recovery after bowel resection regardless of age, gender, race, or concomitant medication use.
4/2007Postoperative ileus-related morbidity profile in patients treated with alvimopan after bowel resection.
3/2007Alvimopan, for postoperative ileus following bowel resection: a pooled analysis of phase III studies.
6/2005Phase III trial of alvimopan, a novel, peripherally acting, mu opioid antagonist, for postoperative ileus after major abdominal surgery.
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Lee Techner Research Topics

Disease

12Ileus
08/2014 - 10/2004
2Pain (Aches)
04/2007 - 03/2005
1Urinary Bladder Neoplasms (Bladder Cancer)
08/2014
1Postoperative Pain
08/2009
1Flatulence
10/2007
1Nausea
06/2005
1Hypotension (Low Blood Pressure)
06/2005
1Vomiting
06/2005
1Opioid-Related Disorders (Opiate Addiction)
03/2005
1Opioid-Induced Constipation
03/2005

Drug/Important Bio-Agent (IBA)

12alvimopanFDA Link
08/2014 - 10/2004
5Opioid Analgesics (Opioids)IBA
08/2014 - 03/2005
5mu Opioid Receptors (mu Opioid Receptor)IBA
05/2012 - 03/2005
2Narcotic Antagonists (Opioid Antagonists)IBA
06/2005 - 10/2004
1Pharmaceutical PreparationsIBA
06/2014
1Opioid Receptors (Opioid Receptor)IBA
03/2005

Therapy/Procedure

5Length of Stay
08/2014 - 06/2005
3Laparotomy
08/2009 - 10/2004
2Cystectomy
08/2014 - 06/2014
2Analgesia
11/2008 - 03/2005
1Total Parenteral Nutrition
06/2014
1Patient-Controlled Analgesia (Analgesia, Patient Controlled)
08/2009
1Colectomy
08/2009
1Postoperative Care
11/2008
1Epidural Anesthesia
10/2007
1Therapeutics
03/2005